Targeted drug delivery to tumors: Myths, reality and possibility

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Targeted drug delivery to tumors: myths, reality and possibility.

The ultimate goal of drug delivery research is to help patients by developing clinically useful formulations. During the last several decades controlled drug delivery technology has advanced significantly, leading to the development of various clinical formulations improving patient compliance and convenience [1]. Current technologies allow delivery of drugs at desired release kinetics for exte...

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Although nanoparticle-based drug delivery formulations can improve the effectiveness and safety of certain anticancer drugs, many drugs, due to their chemical composition, are unsuitable for nanoparticle loading. Here, we describe a targeted nanogel drug delivery platform that can (i) encapsulate a wide range of drug chemotypes, including biological, small molecule, and cytotoxic agents; (ii) d...

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ژورنال

عنوان ژورنال: Journal of Controlled Release

سال: 2011

ISSN: 0168-3659

DOI: 10.1016/j.jconrel.2011.06.001